The atomic force microscope that combines versatility and performance for biology and life science
|Techniques and applications for life science research|
|A design that opens up entirely new possibilities|
|Discover all the practical details that really matter in daily use|
|Discuss your application with one of our application scientists|
A key success factor in life science research is the combination of multiple techniques. With the Flex-Bio, Nanosurf's Bio AFM, you can combine the liquid AFM imaging, spectroscopy and nanomanipulation capacity of this system with the high-end optical techniques available for inverted microscopes.
Techniques and applications for life science research
Flex-Bio comes with manual and motorized stages for seamless integration on Zeiss, Olympus, Nikon and Leica inverted microscopes or with standalone stages. On the inverted microscope, optical and AFM data can be correlated, as shown here for internal limiting membrane (ILM) of the human retina.
For measurements that don’t need optical access from below, e.g. for the imaging and spectroscopy of samples like bacteriorhodopsin, a standalone stage makes the Flex-Bio compatible with the Nanosurf Isostage and Acoustic Enclosure 300, and generally makes the system much more compact.
For more applications, please see the application and publication sections on the right, or visit our Applications page.
A system design that opens up entirely new possibilities
The Flex-Bio has a modular stage, cantilever holder, and software concept that allows an easy upgrade of the system to access many new possibilities in life science and materials research. Flex-FPM for cell and nano-manipulation, for example, and Flex-ANA for automatic nanomechanical analysis. In addition, advanced modes like MFM and KPFM that were originally developed for the Flex-Axiom system, are also available for Flex-Bio.
Practical details that really matter in daily use
Cantilever holders with alignment structures are available for use with cantilevers containing alignment grooves. This provides micrometer repositioning accuracy, circumventing laser alignment and allowing you to find the same sample features again and again. Cantilevers enter the image from top to bottom, so sample orientation is always the same, no matter whether you look by eye, CCD camera, or AFM (when scanned at the default scan angle).
Flex-Bio components and accessories
At the heart of the Flex-Bio system are the FlexAFM scan head and the C3000 controller with I100 interface box. On top of that, several options and accessories are available, designed to deliver stable and reliable results, or to provide access to new measurement possibilities and experiments for this Bio AFM:
|Cantilever holders for AFM in liquid|
|Cover slip holder with heating option|
|Petri dish holder to directly use cell culture dishes as AFM liquid cell|
|Environmental control chambers from several inverted microscope providers and Life Imaging Services (LIS) to support AFM cell imaging under conditions favorable to your cells|
|Large acoustic enclosures and active vibration isolation solutions for the Flex-Bio/inverted microscope setup (e.g. from Accurion)|
Free pre-sales consultancy from one of our experienced application scientists
Contact us now to discuss your bio AFM application.