Flex-ANA — AFM for automated force mapping

Flex-ANA — AFM for force mapping

The perfect tool for fully automated nanomechanical data acquisition and analysis

Automated nanomechanical analysis of large or multiple samples
Measure elasticity, stiffness, adhesion, and indentation according to various models
Intelligent software autonomously handles demanding measurements
Accomodates height differences of up to 5 mm and force curves with up to 100 µm in Z
Analysis software for easy comparison of large and complex data sets included
Ask your question or discuss your application with one of our application scientists!

The Nanosurf Flex-ANA system is an automated solution for AFM-based nanomechanical analysis. It is designed to investigate the nanomechanical properties of materials such as cells, tissues, scaffolds, hydrogels, and polymers on multiple or large samples via force spectroscopy and force mapping in an intuitive and automated fashion.

Nanomechanical analysis of large or multiple samples

The combination of a straight-forward experimental and post-processing workflow, selected hardware elements, and thought-through, well-designed control algorithms are hallmarks of the Flex-ANA system. Measurement locations on large or multiple samples are defined using an overview image with a large field-of-view that covers the entire accessible 32 mm × 32 mm sample area. Height differences of up to 5 mm can be overcome automatically by the system!

Flex-Ana workflow
Schematic Flex-ANA workflow: from measurements to data analysis and comparison (left). Corresponding Flex-ANA measurement software (top right) and analysis software (bottom right).

Intelligent software autonomously deals with demanding samples

During an experiment, smart algorithms coordinate the movement of the scan head and the motorized XYZ translation stage (32 mm × 32 mm × 5 mm range), which can optionally be equipped with an additional 100-µm Z piezo for an extended spectroscopy range. To cope with large sample height variations, proprietary algorithms permanently monitor and optimize the sample position with respect to the probing cantilever and drive all Z elements accordingly. Thus, soft and sticky samples, as well as samples with macroscopic and microscopic roughness in the range of several millimeters and micrometers, respectively, can be easily addressed.

Software for advanced analysis and comparison of large, complex data sets

Besides conducting automated nanomechanical measurements, the Flex-ANA system offers advanced data post-processing and analysis capabilities:

Flex-ANA analysis software
Large data sets are automatically organized and can be batch processed and analyzed using a variety of standard contact mechanics models
individual force curves
Individual force curves inside maps can be reviewed, and proprietary force curve quality control helps exclude data compromised by e.g. undesired sample contact or contamination
custom analysis of results
Results from independent measurements can be analyzed, filtered, and pooled into data sets according to your criteria
compare data sets
Entire data sets can then easily be compared to other data sets and evaluated statistically

Flex-ANA components

FlexAFM scan head
C3000 controller
ATS 204 automated translation stage
Isostage vibration isolation table
5 MP Overview Camera
Dedicated PC for data acquisition and analysis
Flex-ANA measurement and analysis software
Optional 100-µm Z-actuator

Free consultation from one of our experienced application scientists

Contact us now to discuss your project.

The Flex-ANA advantage

Intelligent automation
Intuitive and powerful software
Robust and reliable results

User feedback

  • Dr. Dalia Yablon

    Dr. Dalia Yablon

    I really enjoy using the Flex-ANA for its force mapping capabilities on polymer materials. The scientists at Nanosurf are hi...

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