Flex-ANA — AFM for automated force mapping

Flex-ANA — AFM for force mapping

The perfect tool for fully automated nanomechanical data acquisition and analysis

Automated nanomechanical analysis of large or multiple samples
Measure elasticity, stiffness, adhesion, and indentation according to various models
Accomodates height differences of up to 5 mm and force curves with up to 100 µm in Z
Powerful measurements and meaningful analyses for experts and novices alike

The Nanosurf Flex-ANA system is an automated solution for AFM-based nanomechanical analysis. It is designed to investigate the nanomechanical properties of materials such as cells, tissues, scaffolds, hydrogels, and polymers on multiple or large samples via force spectroscopy and force mapping in an intuitive and automated fashion.

Nanomechanical analysis of large or multiple samples

The combination of a straight-forward workflow-based experimental procedure in the Flex-ANA software, carefully selected hardware elements and motorization, and well-designed and thought-through control algorithms are hallmarks of the Flex-ANA system. Measurement locations on large or multiple samples are defined by simply clicking on an overview image with a large field-of-view that covers the entire accessible 32 mm × 32 mm sample area. Height differences of up to 5 mm can be easily overcome by the system, and many types of nanomechanical measurements, analyses and models can be performed and used!

The Flex-ANA software during measurement. The software provides a clearly structured interface, readily showing the parameters of interest as live force curves, histograms, and heat maps during the measurement. The current measurement location is indicated in the optical overview image.

Handle demanding samples with ease

During an experiment, the Flex-ANA system coordinates the movement of the scan head and the motorized XYZ translation stage (range: 32 mm × 32 mm × 5 mm) to cope with large sample height variations. The system can optionally be equipped with an additional 100-µm Z piezo for an extended force spectroscopy range. Thus, samples with macroscopic and microscopic roughness in the range of several millimeters and micrometers, respectively, as well as soft and sticky samples, can be easily addressed.

Operation by experts as well as novice users

The Flex-ANA control software provides a Basic and an Expert user mode that are designed for different degrees of user experience and training:

In Basic mode, less experienced users are guided through the setup and calibration of the Flex-ANA system step-by-step. Optimized workflows guarantee that everything is done in the correct sequence, that nothing is forgotten, and that all is set properly.

In Expert mode, experienced users have more freedom in operating and setting up the system to suit their individual needs. Measurement parameters can also be prepared and stored by an expert, and then subsequently used by less experienced users in Basic mode.

Flex-ANA components

FlexAFM scan head
C3000 controller
ATS 204 automated translation stage
Isostage vibration isolation table
5 MP Overview Camera
Dedicated PC for data acquisition and analysis
Flex-ANA measurement and analysis software
Optional 100-µm Z-actuator

Free consultation from one of our experienced application scientists

Contact us now to discuss your project.

The Flex-ANA advantage

Intelligent automation
Intuitive and powerful software
Robust and reliable results

User feedback

  • Dr. Dalia Yablon

    Dr. Dalia Yablon

    I really enjoy using the Flex-ANA for its force mapping capabilities on polymer materials. The scientists at Nanosurf are hi...

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